LMPD Database

LMP010555

UniProt Annotations

Entry Information
Gene Namelipoxygenase 3
Protein EntryLOX3_ARATH
UniProt IDQ9LNR3
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityAlpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13- hydroperoxyoctadeca-9,11,15-trienoate.
Catalytic ActivityLinoleate + O(2) = (9Z,11E,13S)-13- hydroperoxyoctadeca-9,11-dienoate.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000255|PROSITE-ProRule:PRU00726}; Note=Binds 1 Fe cation per subunit. {ECO:0000255|PROSITE- ProRule:PRU00726};
Developmental StageFirst observed in lateral root primordia (LRP), from the first pericycle divisions. Later expressed in lateral roots. Expression is greatly increased in leaves during leaf senescence. {ECO:0000269|PubMed:11891244, ECO:0000269|PubMed:17369372}.
Function13S-lipoxygenase that can use linolenic acid as substrates. Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity). {ECO:0000250}.
InductionInduced by methyl jasmonate (MeJA), bacterial pathogens (e.g. Pseudomonas syringae pv. tomato), high light and wounding. {ECO:0000269|PubMed:17786451, ECO:0000269|PubMed:18156220, ECO:0000269|PubMed:18216250}.
PathwayLipid metabolism; oxylipin biosynthesis. {ECO:0000255|PROSITE-ProRule:PRU00726}.
Sequence CautionSequence=AAF97315.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the lipoxygenase family. {ECO:0000305}.
SimilarityContains 1 lipoxygenase domain. {ECO:0000255|PROSITE- ProRule:PRU00726}.
SimilarityContains 1 PLAT domain. {ECO:0000255|PROSITE- ProRule:PRU00152}.
Subcellular LocationPlastid, chloroplast {ECO:0000305}.
Tissue SpecificityExpressed in roots and leaves. {ECO:0000269|PubMed:17369372}.