LMPD Database

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LMP006799

UniProt Annotations

Entry Information
Gene Namelipoyltransferase 1
Protein EntryLIPT_HUMAN
UniProt IDQ9Y234
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityLipoyl-AMP + protein = protein N(6)- (lipoyl)lysine + AMP.
FunctionCatalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes.
PathwayProtein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.
SimilarityBelongs to the LplA family.
SimilarityContains 1 BPL/LPL catalytic domain.
Subcellular LocationMitochondrion.
Tissue SpecificityHighly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung.