LMPD Database

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LMP006728

UniProt Annotations

Entry Information
Gene Namestearoyl-CoA desaturase 5
Protein EntrySCD5_HUMAN
UniProt IDQ86SK9
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86SK9-1; Sequence=Displayed; Name=2; IsoId=Q86SK9-2; Sequence=VSP_029883; Note=No experimental confirmation available.;
Catalytic ActivityStearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.
CofactorName=Fe cation; Xref=ChEBI
DomainThe histidine box domains may contain the active site and/or be involved in metal ion binding.
FunctionFatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position.
SimilarityBelongs to the fatty acid desaturase family.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue SpecificityDetected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung. {ECO