LMPD Database

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LMP006621

Record overview

LMPD IDLMP006621
Gene ID54928
SpeciesHomo sapiens (Human)
Gene Nameinositol monophosphatase domain containing 1
Gene SymbolIMPAD1
SynonymsGPAPP; IMP 3; IMP-3; IMPA3
Alternate namesinositol monophosphatase 3; IMPase 3; golgi-resident PAP phosphatase; myo-inositol monophosphatase A3; inositol-1(or 4)-monophosphatase 3; inositol monophosphatase domain-containing protein 1; Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase
Chromosome8
Map Location8q12.1
EC Number3.1.3.25
SummaryThis gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, Dec 2011]
OrthologsView orthologs and multiple alignments for IMPAD1

Proteins

inositol monophosphatase 3
Refseq ID:NP_060283
Protein GI:157388900
UniProt ID:Q9NX62
mRNA ID:NM_017813
Length:359
RefSeq Status:REVIEWED
MAPMGIRLSPLGVAVFCLLGLGVLYHLYSGFLAGRFSLFGLGGEPGGGAAGPAAAADGGTVDLREMLAVSVLAAVRGGDEVRRVRESNVLHEKSKGKTRE
GAEDKMTSGDVLSNRKMFYLLKTAFPSVQINTEEHVDAADQEVILWDHKIPEDILKEVTTPKEVPAESVTVWIDPLDATQEYTEDLRKYVTTMVCVAVNG
KPMLGVIHKPFSEYTAWAMVDGGSNVKARSSYNEKTPRIVVSRSHSGMVKQVALQTFGNQTTIIPAGGAGYKVLALLDVPDKSQEKADLYIHVTYIKKWD
ICAGNAILKALGGHMTTLSGEEISYTGSDGIEGGLLASIRMNHQALVRKLPDLEKTGHK