LMPD Database

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LMP006180

UniProt Annotations

Entry Information
Gene Namesphingosine-1-phosphate phosphatase 1
Protein EntrySGPP1_HUMAN
UniProt IDQ9BX95
SpeciesHuman
Comments
Comment typeDescription
FunctionHas enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels.
SimilarityBelongs to the type 2 lipid phosphate phosphatase family.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue SpecificityUbiquitous, with the strongest level in placenta and kidney.