LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP006180

Record overview

LMPD IDLMP006180
Gene ID81537
SpeciesHomo sapiens (Human)
Gene Namesphingosine-1-phosphate phosphatase 1
Gene SymbolSGPP1
SynonymsSPPase1
Alternate namessphingosine-1-phosphate phosphatase 1; spp1; hSPP1; hSPPase1; sphingosine-1-phosphatase 1
Chromosome14
Map Location14q23.2
EC Number3.1.3.-
SummarySphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]
OrthologsView orthologs and multiple alignments for SGPP1

Proteins

sphingosine-1-phosphate phosphatase 1
Refseq ID:NP_110418
Protein GI:13540569
UniProt ID:Q9BX95
mRNA ID:NM_030791
Length:441
RefSeq Status:PROVISIONAL
MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPA
SPRRAGALRRNSLTGEEGQLARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNS
EYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHL
ALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCD
DIRKARQHMEVELPYRYITYGMVGFSITFFVPYIFFFIGIS