LMPD Database

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LMP005684

Record overview

LMPD IDLMP005684
Gene ID107817
SpeciesMus musculus(Mouse)
Gene Namejumonji domain containing 6
Gene SymbolJmjd6
Synonyms5730436I23Rik; D11Ertd195e; PSR; PtdSerR; Ptdsr; mKIAA0585
Alternate namesbifunctional arginine demethylase and lysyl-hydroxylase JMJD6; lysyl-hydroxylase JMJD6; phosphatidylserine receptor; jmjC domain-containing protein 6; histone arginine demethylase JMJD6; peptide-lysine 5-dioxygenase JMJD6; jumonji domain-containing protein 6; apoptotic cell clearance receptor PtdSerR
Chromosome11
Map Location11 E2|11 81.49 cM
EC Number1.14.11.-
SummaryThis gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein functions in differentiation of multiple tissues during development, and in anti-inflammatory cytokine signaling. It was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that this protein does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for Jmjd6

Proteins

bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Refseq ID:NP_203971
Protein GI:125988379
UniProt ID:Q9ERI5
mRNA ID:NM_033398
Length:403
RefSeq Status:REVIEWED
MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESYPLNPAAVPDNVERADALQLSVKEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFK
CGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALV
QGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHK
TVRGRPKLSRKWYRILKQEHPELAVLADAVDLQESTGIASDSSSDSSSSSSSSSSDSDSECESGSEGDGTTHRRKKRRTCSMVGNGDTTSQDDCVSKERS
SSR