LMPD Database

LMP005600

Gene Information

Entrez Gene ID	8029
Gene Name	cubilin (intrinsic factor-cobalamin receptor)
Gene Symbol	CUBN
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016324	IDA:UniProt	C	apical plasma membrane
GO:0031526	NAS:UniProtKB	C	brush border membrane
GO:0005905	IEA:Ensembl	C	coated pit
GO:0005829	TAS:Reactome	C	cytosol
GO:0030139	IDA:UniProt	C	endocytic vesicle
GO:0005783	IEA:Ensembl	C	endoplasmic reticulum
GO:0010008	TAS:Reactome	C	endosome membrane
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0031232	NAS:UniProtKB	C	extrinsic component of external side of plasma membrane
GO:0005794	IEA:Ensembl	C	Golgi apparatus
GO:0043202	TAS:Reactome	C	lysosomal lumen
GO:0016020	TAS:ProtInc	C	membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0005509	IEA:InterPro	F	calcium ion binding
GO:0031419	IEA:UniProtKB-KW	F	cobalamin binding
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0004872	TAS:ProtInc	F	receptor activity
GO:0005215	TAS:ProtInc	F	transporter activity
GO:0008203	IEA:UniProtKB-KW	P	cholesterol metabolic process
GO:0009235	TAS:Reactome	P	cobalamin metabolic process
GO:0015889	TAS:ProtInc	P	cobalamin transport
GO:0042157	TAS:Reactome	P	lipoprotein metabolic process
GO:0042953	IEA:Ensembl	P	lipoprotein transport
GO:0006898	NAS:UniProtKB	P	receptor-mediated endocytosis
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0008202	TAS:Reactome	P	steroid metabolic process
GO:0001894	NAS:UniProtKB	P	tissue homeostasis
GO:0042359	TAS:Reactome	P	vitamin D metabolic process
GO:0006766	TAS:Reactome	P	vitamin metabolic process
GO:0006767	TAS:Reactome	P	water-soluble vitamin metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04977	Vitamin digestion and absorption

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_163862	Cobalamin (Cbl, vitamin B12) transport and metabolism
REACT_13621	HDL-mediated lipid transport
REACT_13523	Vitamin D (calciferol) metabolism