LMPD Database

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LMP003016

UniProt Annotations

Entry Information
Gene Nameproteolipid protein 2 (colonic epithelium-enriched)
Protein EntryPLP2_HUMAN
UniProt IDQ04941
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q04941-1; Sequence=Displayed; Name=2; IsoId=Q04941-2; Sequence=VSP_041602;
FunctionMay play a role in cell differentiation in the intestinal epithelium.
InteractionP32246:CCR1; NbExp=3; IntAct=EBI-608347, EBI-608322;
SimilarityContains 1 MARVEL domain. {ECO
Subcellular LocationMembrane; Multi-pass membrane protein.
Tissue SpecificityEnriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.