LMPD Database

LMP003016

Record overview

LMPD IDLMP003016
Gene ID5355
SpeciesHomo sapiens (Human)
Gene Nameproteolipid protein 2 (colonic epithelium-enriched)
Gene SymbolPLP2
SynonymsA4; A4LSB
Alternate namesproteolipid protein 2; intestinal membrane A4 protein; A4 differentiation-dependent protein; differentiation-dependent protein A4
ChromosomeX
Map LocationXp11.23
SummaryThis gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]
OrthologsView orthologs and multiple alignments for PLP2

Proteins

proteolipid protein 2
Refseq ID:NP_002659
Protein GI:4505893
UniProt ID:Q04941
mRNA ID:NM_002668
Length:152
RefSeq Status:REVIEWED
MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSI
VVLVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV