LMPD Database

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LMP002953

Gene Information

Entrez Gene ID19211
Gene Namephosphatase and tensin homolog
Gene SymbolPten
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0009898 IEA:EnsemblCcytoplasmic side of plasma membrane
GO:0043197 IEA:EnsemblCdendritic spine
GO:0005739 IEA:EnsemblCmitochondrion
GO:0035749 IDA:BHF-UCLCmyelin sheath adaxonal region
GO:0043005 IDA:BHF-UCLCneuron projection
GO:0005634 IDA:MGICnucleus
GO:0045211 IEA:EnsemblCpostsynaptic membrane
GO:0043220 IDA:BHF-UCLCSchmidt-Lanterman incisure
GO:0051717 ISS:UniProtKBFinositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
GO:0000287 IEA:InterProFmagnesium ion binding
GO:0030165 ISS:UniProtKBFPDZ domain binding
GO:0016314 ISS:UniProtKBFphosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0051800 ISS:UniProtKBFphosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
GO:0004438 ISS:UniProtKBFphosphatidylinositol-3-phosphatase activity
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0004722 ISS:UniProtKBFprotein serine/threonine phosphatase activity
GO:0004725 ISS:UniProtKBFprotein tyrosine phosphatase activity
GO:0008138 IEA:InterProFprotein tyrosine/serine/threonine phosphatase activity
GO:0007092 IMP:BHF-UCLPactivation of mitotic anaphase-promoting complex activity
GO:0007568 IEA:EnsemblPaging
GO:0001525 IMP:MGIPangiogenesis
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0048854 IMP:BHF-UCLPbrain morphogenesis
GO:0060070 IEA:EnsemblPcanonical Wnt signaling pathway
GO:0048738 IMP:MGIPcardiac muscle tissue development
GO:0016477 IMP:MGIPcell migration
GO:0007417 IMP:MGIPcentral nervous system development
GO:0032286 IMP:BHF-UCLPcentral nervous system myelin maintenance
GO:0021955 IMP:BHF-UCLPcentral nervous system neuron axonogenesis
GO:0060997 IMP:BHF-UCLPdendritic spine morphogenesis
GO:0021542 IMP:BHF-UCLPdentate gyrus development
GO:0043542 IMP:MGIPendothelial cell migration
GO:0048853 IMP:BHF-UCLPforebrain morphogenesis
GO:0007507 IMP:MGIPheart development
GO:0046855 ISS:UniProtKBPinositol phosphate dephosphorylation
GO:0007611 IMP:BHF-UCLPlearning or memory
GO:0045475 IMP:BHF-UCLPlocomotor rhythm
GO:0007626 IMP:BHF-UCLPlocomotory behavior
GO:0060292 IEA:EnsemblPlong term synaptic depression
GO:0060291 IMP:BHF-UCLPlong-term synaptic potentiation
GO:0060179 IMP:BHF-UCLPmale mating behavior
GO:0042711 IMP:BHF-UCLPmaternal behavior
GO:0007613 IEA:EnsemblPmemory
GO:0033555 IMP:BHF-UCLPmulticellular organismal response to stress
GO:0043066 IMP:UniProtKBPnegative regulation of apoptotic process
GO:0050771 IMP:BHF-UCLPnegative regulation of axonogenesis
GO:0090344 IMP:BHF-UCLPnegative regulation of cell aging
GO:0030336 ISS:UniProtKBPnegative regulation of cell migration
GO:0008285 ISS:UniProtKBPnegative regulation of cell proliferation
GO:0045792 IMP:BHF-UCLPnegative regulation of cell size
GO:0031658 IEA:EnsemblPnegative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0061002 IMP:BHF-UCLPnegative regulation of dendritic spine morphogenesis
GO:0050680 IMP:MGIPnegative regulation of epithelial cell proliferation
GO:0090394 IMP:BHF-UCLPnegative regulation of excitatory postsynaptic membrane potential
GO:0051895 ISS:UniProtKBPnegative regulation of focal adhesion assembly
GO:2000134 IEA:EnsemblPnegative regulation of G1/S transition of mitotic cell cycle
GO:0031642 IMP:MGIPnegative regulation of myelination
GO:0046621 IMP:BHF-UCLPnegative regulation of organ growth
GO:0050765 IEA:EnsemblPnegative regulation of phagocytosis
GO:0051898 IMP:UniProtKBPnegative regulation of protein kinase B signaling
GO:0090071 IMP:BHF-UCLPnegative regulation of ribosome biogenesis
GO:2000808 IMP:BHF-UCLPnegative regulation of synaptic vesicle clustering
GO:0007270 IMP:BHF-UCLPneuron-neuron synaptic transmission
GO:0035335 ISS:GOCPpeptidyl-tyrosine dephosphorylation
GO:0046856 ISS:UniProtKBPphosphatidylinositol dephosphorylation
GO:0048008 IEA:EnsemblPplatelet-derived growth factor receptor signaling pathway
GO:0043065 IEA:EnsemblPpositive regulation of apoptotic process
GO:2001235 IMP:MGIPpositive regulation of apoptotic signaling pathway
GO:0008284 IMP:BHF-UCLPpositive regulation of cell proliferation
GO:2000463 IMP:BHF-UCLPpositive regulation of excitatory postsynaptic membrane potential
GO:2000060 IEA:EnsemblPpositive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051091 IEA:EnsemblPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0097107 IMP:BHF-UCLPpostsynaptic density assembly
GO:0060134 IMP:BHF-UCLPprepulse inhibition
GO:0097105 IMP:BHF-UCLPpresynaptic membrane assembly
GO:0060736 IMP:MGIPprostate gland growth
GO:0006470 ISS:UniProtKBPprotein dephosphorylation
GO:0043491 IMP:UniProtKBPprotein kinase B signaling
GO:0050821 IEA:EnsemblPprotein stabilization
GO:0002902 IMP:MGIPregulation of B cell apoptotic process
GO:0051726 IGI:MGIPregulation of cell cycle
GO:0032535 IMP:BHF-UCLPregulation of cellular component size
GO:0033032 IMP:MGIPregulation of myeloid cell apoptotic process
GO:0010975 IMP:UniProtKBPregulation of neuron projection development
GO:0031647 ISS:UniProtKBPregulation of protein stability
GO:0046685 IEA:EnsemblPresponse to arsenic-containing substance
GO:0033198 IEA:EnsemblPresponse to ATP
GO:0042493 IEA:EnsemblPresponse to drug
GO:0032355 IEA:EnsemblPresponse to estradiol
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0009749 IEA:EnsemblPresponse to glucose
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0010043 IEA:EnsemblPresponse to zinc ion
GO:0060024 IMP:BHF-UCLPrhythmic synaptic transmission
GO:0035176 IMP:BHF-UCLPsocial behavior
GO:0007416 IMP:BHF-UCLPsynapse assembly
GO:0060074 IMP:BHF-UCLPsynapse maturation
KEGG Pathway Links
KEGG Pathway IDDescription
mmu04068FoxO signaling pathway
mmu05161Hepatitis B
mmu05206MicroRNAs in cancer
mmu04151PI3K-Akt signaling pathway