LMPD Database

LMP002851

UniProt Annotations

Entry Information

Gene Name	solute carrier family 10 (sodium/bile acid cotransporter), member 2
Protein Entry	NTCP2_HUMAN
UniProt ID	Q12908
Species	Human

Comments

Comment type	Description
Disease	Primary bile acid malabsorption (PBAM) [MIM
Function	Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
Similarity	Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Subcellular Location	Membrane; Multi-pass membrane protein.
Subunit	Monomer and homodimer.