LMPD Database

LMP002632

Gene Information

Entrez Gene ID	1586
Gene Name	cytochrome P450, family 17, subfamily A, polypeptide 1
Gene Symbol	CYP17A1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030424	IEA:Ensembl	C	axon
GO:0005783	NAS:ProtInc	C	endoplasmic reticulum
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0047442	IEA:UniProtKB-EC	F	17-alpha-hydroxyprogesterone aldolase activity
GO:0020037	IDA:UniProtKB	F	heme binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0019825	TAS:ProtInc	F	oxygen binding
GO:0004508	IDA:UniProtKB	F	steroid 17-alpha-monooxygenase activity
GO:0030325	IEA:Ensembl	P	adrenal gland development
GO:0006702	TAS:Reactome	P	androgen biosynthetic process
GO:0018879	IEA:Ensembl	P	biphenyl metabolic process
GO:0071236	IEA:Ensembl	P	cellular response to antibiotic
GO:0071371	IEA:Ensembl	P	cellular response to gonadotropin stimulus
GO:0071222	IEA:Ensembl	P	cellular response to lipopolysaccharide
GO:0018894	IEA:Ensembl	P	dibenzo-p-dioxin metabolic process
GO:0006704	TAS:Reactome	P	glucocorticoid biosynthetic process
GO:0021766	IEA:Ensembl	P	hippocampus development
GO:0042446	IDA:UniProtKB	P	hormone biosynthetic process
GO:0033327	IEA:Ensembl	P	Leydig cell differentiation
GO:0030728	IEA:Ensembl	P	ovulation
GO:0018958	IEA:Ensembl	P	phenol-containing compound metabolic process
GO:0018963	IEA:Ensembl	P	phthalate metabolic process
GO:0090031	IEA:Ensembl	P	positive regulation of steroid hormone biosynthetic process
GO:0042448	IDA:UniProtKB	P	progesterone metabolic process
GO:0010034	IEA:Ensembl	P	response to acetate
GO:0051591	IEA:Ensembl	P	response to cAMP
GO:0034097	IEA:Ensembl	P	response to cytokine
GO:0042493	IEA:Ensembl	P	response to drug
GO:0060992	IEA:Ensembl	P	response to fungicide
GO:0009635	IEA:Ensembl	P	response to herbicide
GO:0017085	IEA:Ensembl	P	response to insecticide
GO:0010212	IEA:Ensembl	P	response to ionizing radiation
GO:0051597	IEA:Ensembl	P	response to methylmercury
GO:0031667	IEA:Ensembl	P	response to nutrient levels
GO:0032526	IEA:Ensembl	P	response to retinoic acid
GO:0048545	IEA:Ensembl	P	response to steroid hormone
GO:0007548	TAS:ProtInc	P	sex differentiation
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006694	TAS:ProtInc	P	steroid biosynthetic process
GO:0008202	IDA:UniProtKB	P	steroid metabolic process
GO:0016125	TAS:Reactome	P	sterol metabolic process
GO:0006805	TAS:Reactome	P	xenobiotic metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04913	Ovarian steroidogenesis
hsa04917	Prolactin signaling pathway
hsa00140	Steroid hormone biosynthesis