LMPD Database

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LMP002559

UniProt Annotations

Entry Information
Gene Nameglutathione peroxidase 5
Protein EntryGPX5_HUMAN
UniProt IDO75715
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O75715-1; Sequence=Displayed; Name=2; IsoId=O75715-2; Sequence=VSP_043046; Note=No experimental confirmation available.;
Catalytic Activity2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
FunctionProtects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
SimilarityBelongs to the glutathione peroxidase family.
Subcellular LocationSecreted.
Tissue SpecificityEpididymis.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/gpx5/";