LMPD Database

LMP002476

Gene Information

Entrez Gene ID	16835
Gene Name	low density lipoprotein receptor
Gene Symbol	Ldlr
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	ISS:UniProtKB	C	cell surface
GO:0005905	IEA:UniProtKB-KW	C	coated pit
GO:0005769	ISS:UniProtKB	C	early endosome
GO:0005768	IDA:MGI	C	endosome
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0005794	ISS:UniProtKB	C	Golgi apparatus
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005770	ISS:UniProtKB	C	late endosome
GO:0034362	IEA:UniProtKB-KW	C	low-density lipoprotein particle
GO:0005764	ISS:UniProtKB	C	lysosome
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0043235	ISO:MGI	C	receptor complex
GO:0005509	IEA:InterPro	F	calcium ion binding
GO:0030169	IDA:MGI	F	low-density lipoprotein particle binding
GO:0005041	IDA:MGI	F	low-density lipoprotein receptor activity
GO:0030229	IDA:MGI	F	very-low-density lipoprotein particle receptor activity
GO:0042632	IMP:MGI	P	cholesterol homeostasis
GO:0070508	IMP:BHF-UCL	P	cholesterol import
GO:0008203	IMP:MGI	P	cholesterol metabolic process
GO:0030301	IMP:MGI	P	cholesterol transport
GO:0030299	IEA:Ensembl	P	intestinal cholesterol absorption
GO:0006629	IGI:MGI	P	lipid metabolic process
GO:0042159	IDA:MGI	P	lipoprotein catabolic process
GO:0042157	IGI:MGI	P	lipoprotein metabolic process
GO:0034383	IMP:BHF-UCL	P	low-density lipoprotein particle clearance
GO:0015914	IMP:BHF-UCL	P	phospholipid transport
GO:0010867	IMP:BHF-UCL	P	positive regulation of triglyceride biosynthetic process
GO:0006898	IDA:GOC	P	receptor-mediated endocytosis
GO:2000188	IMP:MGI	P	regulation of cholesterol homeostasis
GO:0010899	IMP:BHF-UCL	P	regulation of phosphatidylcholine catabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04913	Ovarian steroidogenesis