LMPD Database

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LMP002433

Gene Information

Entrez Gene ID242
Gene Namearachidonate 12-lipoxygenase, 12R type
Gene SymbolALOX12B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0004052 IMP:UniProtKBFarachidonate 12-lipoxygenase activity
GO:0005506 IEA:InterProFiron ion binding
GO:1990136 ISS:UniProtKBFlinoleate 9S-lipoxygenase activity
GO:0016702 IDA:UniProtKBFoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019369 IMP:UniProtKBParachidonic acid metabolic process
GO:0046513 ISS:UniProtKBPceramide biosynthetic process
GO:0061436 ISS:UniProtKBPestablishment of skin barrier
GO:0051122 ISS:UniProtKBPhepoxilin biosynthetic process
GO:0043651 ISS:UniProtKBPlinoleic acid metabolic process
GO:0019372 IDA:UniProtKBPlipoxygenase pathway
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0010628 IMP:UniProtKBPpositive regulation of gene expression
GO:0043410 IDA:UniProtKBPpositive regulation of MAPK cascade
GO:0070257 IMP:UniProtKBPpositive regulation of mucus secretion
GO:0006497 ISS:UniProtKBPprotein lipidation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 IDA:UniProtKBPsphingolipid metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00590Arachidonic acid metabolism
hsa04726Serotonergic synapse
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_150201Synthesis of 12-eicosatetraenoic acid derivatives