LMPD Database

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LMP002290

Gene Information

Entrez Gene ID228026
Gene Namepyruvate dehydrogenase kinase, isoenzyme 1
Gene SymbolPdk1
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005967 IDA:UniProtKBCmitochondrial pyruvate dehydrogenase complex
GO:0005739 IDA:MGICmitochondrion
GO:0005886 ISA:MGICplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004674 IEA:UniProtKB-KWFprotein serine/threonine kinase activity
GO:0004740 ISS:UniProtKBFpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0008283 ISS:UniProtKBPcell proliferation
GO:0006006 IEA:UniProtKB-KWPglucose metabolic process
GO:0097411 ISS:UniProtKBPhypoxia-inducible factor-1alpha signaling pathway
GO:0035556 ISA:MGIPintracellular signal transduction
GO:0008631 ISS:UniProtKBPintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0006468 ISS:GOCPprotein phosphorylation
GO:0010510 IMP:UniProtKBPregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 ISS:UniProtKBPregulation of glucose metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
mmu04066HIF-1 signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5893557Regulation of pyruvate dehydrogenase (PDH) complex