LMPD Database

LMP001878

Gene Information

Entrez Gene ID2879
Gene Nameglutathione peroxidase 4
Gene SymbolGPX4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005739 TAS:UniProtKBCmitochondrion
GO:0005635 IEA:EnsemblCnuclear envelope
GO:0005634 IDA:UniProtCnucleus
GO:0043295 IEA:EnsemblFglutathione binding
GO:0004602 TAS:UniProtKBFglutathione peroxidase activity
GO:0047066 IEA:UniProtKB-ECFphospholipid-hydroperoxide glutathione peroxidase activity
GO:0008430 IEA:EnsemblFselenium binding
GO:0007568 IEA:EnsemblPaging
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0006325 IEA:EnsemblPchromatin organization
GO:0006749 IEA:EnsemblPglutathione metabolic process
GO:0042744 IEA:EnsemblPhydrogen peroxide catabolic process
GO:0019372 TAS:ReactomePlipoxygenase pathway
GO:0007275 IEA:UniProtKB-KWPmulticellular organismal development
GO:0055114 TAS:UniProtKBPoxidation-reduction process
GO:0006644 TAS:UniProtKBPphospholipid metabolic process
GO:0050727 IEA:EnsemblPregulation of inflammatory response
GO:0032355 IEA:EnsemblPresponse to estradiol
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007283 IEA:EnsemblPspermatogenesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150201Synthesis of 12-eicosatetraenoic acid derivatives
REACT_150422Synthesis of 15-eicosatetraenoic acid derivatives
REACT_150209Synthesis of 5-eicosatetraenoic acids