LMPD Database

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LMP001844

Gene Information

Entrez Gene ID241
Gene Namearachidonate 5-lipoxygenase-activating protein
Gene SymbolALOX5AP
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IEA:EnsemblCcytosol
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005635 IDA:UniProtKBCnuclear envelope
GO:0031965 IDA:UniProtKBCnuclear membrane
GO:0050544 IDA:UniProtKBFarachidonic acid binding
GO:0008047 IEA:InterProFenzyme activator activity
GO:0047485 IPI:UniProtKBFprotein N-terminus binding
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0071277 IDA:UniProtKBPcellular response to calcium ion
GO:0019370 IDA:UniProtKBPleukotriene biosynthetic process
GO:0006691 TAS:ReactomePleukotriene metabolic process
GO:0002540 IEA:EnsemblPleukotriene production involved in inflammatory response
GO:2001300 TAS:ReactomePlipoxin metabolic process
GO:0019372 TAS:ReactomePlipoxygenase pathway
GO:0002675 IEA:EnsemblPpositive regulation of acute inflammatory response
GO:0070207 IPI:UniProtKBPprotein homotrimerization
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150209Synthesis of 5-eicosatetraenoic acids
REACT_150420Synthesis of Leukotrienes (LT) and Eoxins (EX)
REACT_150320Synthesis of Lipoxins (LX)