LMPD Database

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LMP001404

UniProt Annotations

Entry Information
Gene Namemalonyl CoA:ACP acyltransferase (mitochondrial)
Protein EntryFABD_HUMAN
UniProt IDQ8IVS2
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8IVS2-1; Sequence=Displayed; Name=2; IsoId=Q8IVS2-2; Sequence=VSP_010517, VSP_010518;
Catalytic ActivityMalonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].
FunctionCatalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias.
PathwayLipid metabolism; fatty acid biosynthesis.
SimilarityBelongs to the type II malonyltransferase family.
Subcellular LocationMitochondrion .