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LMP000765

Record overview

LMPD IDLMP000765
Gene ID64064
SpeciesHomo sapiens (Human)
Gene Name3-oxoacid CoA transferase 2
Gene SymbolOXCT2
SynonymsSCOTT
Alternate namessuccinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial; 3-oxoacid CoA-transferase 2A; 3-oxoacid-CoA transferase 2A; testis-specific succinyl CoA:3-oxoacid CoA-transferase; testis-specific succinyl-CoA:3-oxoacid CoA-transferase; succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial
Chromosome1
Map Location1p34
EC Number2.8.3.5
SummaryOXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1 (MIM 601424).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for OXCT2

Proteins

succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial precursor
Refseq ID:NP_071403
Protein GI:11545841
UniProt ID:Q9BYC2
mRNA ID:NM_022120
Length:517
RefSeq Status:PROVISIONAL
MAALRLLASVLGRGVPAGGSGLALSQGCARCFATSPRLRAKFYADPVEMVKDISDGATVMIGGFGLCGIPENLIAALLRTRVKDLQVVSSNVGVEDFGLG
LLLAARQVRRIVCSYVGENTLCESQYLAGELELELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGAPIRYTPDGHLALMSQPREVREFNGDHFLLE
RAIRADFALVKGWKADRAGNVVFRRSARNFNVPMCKAADVTAVEVEEIVEVGAFPPEDIHVPNIYVDRVIKGQKYEKRIERLTILKEEDGDAGKEEDART
RIIRRAALEFEDGMYANLGIGIPLLASNFISPSMTVHLHSENGILGLGPFPTEDEVDADLINAGKQTVTVLPGGCFFASDDSFAMIRGGHIQLTMLGAMQ
VSKYGDLANWMIPGKKVKGMGGAMDLVSSQKTRVVVTMQHCTKDNTPKIMEKCTMPLTGKRCVDRIITEKAVFDVHRKKELTLRELWEGLTVDDIKKSTG
CAFAVSPNLRPMQQVAP
 
transit_peptide: 1..39
inference: non-experimental evidence, no additional details recorded
note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (Q9BYC2.2)
calculated_mol_wt: 3886
peptide sequence: 
MAALRLLASVLGRGVPAGGSGLALSQGCARCFATSPRLR

mat_peptide: 40..517
product: Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9BYC2.2)
calculated_mol_wt: 52273
peptide sequence: 
AKFYADPVEMVKDISDGATVMIGGFGLCGIPENLIAALLRTRVKDLQVVSSNVGVEDFGLGLLLAARQVRRIVCSYVGENTLCESQYLAGELELELTPQG
TLAERIRAGGAGVPAFYTPTGYGTLVQEGGAPIRYTPDGHLALMSQPREVREFNGDHFLLERAIRADFALVKGWKADRAGNVVFRRSARNFNVPMCKAAD
VTAVEVEEIVEVGAFPPEDIHVPNIYVDRVIKGQKYEKRIERLTILKEEDGDAGKEEDARTRIIRRAALEFEDGMYANLGIGIPLLASNFISPSMTVHLH
SENGILGLGPFPTEDEVDADLINAGKQTVTVLPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMIPGKKVKGMGGAMDLVSSQKTRVVVTMQ
HCTKDNTPKIMEKCTMPLTGKRCVDRIITEKAVFDVHRKKELTLRELWEGLTVDDIKKSTGCAFAVSPNLRPMQQVAP