LMPD Database

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LMP000599

Gene Information

Entrez Gene ID9420
Gene Namecytochrome P450, family 7, subfamily B, polypeptide 1
Gene SymbolCYP7B1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0033783 IEA:UniProtKB-ECF25-hydroxycholesterol 7alpha-hydroxylase activity
GO:0020037 IEA:InterProFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0008396 TAS:ProtIncFoxysterol 7-alpha-hydroxylase activity
GO:0006699 TAS:ReactomePbile acid biosynthetic process
GO:0008206 TAS:ReactomePbile acid metabolic process
GO:0008219 IEA:UniProtKB-KWPcell death
GO:0008203 IEA:UniProtKB-KWPcholesterol metabolic process
GO:0033147 IEA:EnsemblPnegative regulation of intracellular estrogen receptor signaling pathway
GO:0050679 IEA:EnsemblPpositive regulation of epithelial cell proliferation
GO:0060740 IEA:EnsemblPprostate gland epithelium morphogenesis
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0016125 TAS:ReactomePsterol metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00120Primary bile acid biosynthesis
hsa00140Steroid hormone biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11048Synthesis of bile acids and bile salts via 27-hydroxycholesterol