LMPD Database

LMP000503

UniProt Annotations

Entry Information

Comments

Comment type	Description
Disease	Note=Defects in Lep are the cause of profound obesity and type II diabetes.
Function	May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Similarity	Belongs to the leptin family. {ECO:0000305}.
Subcellular Location	Secreted {ECO:0000305}.