LMPD Database

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LMP000478

Gene Information

Entrez Gene ID9971
Gene Namenuclear receptor subfamily 1, group H, member 4
Gene SymbolNR1H4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005719 IDA:BHF-UCLCnuclear euchromatin
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0032052 ISS:BHF-UCLFbile acid binding
GO:0038181 IDA:UniProtKBFbile acid receptor activity
GO:1902122 IDA:UniProtKBFchenodeoxycholic acid binding
GO:0004879 ISS:BHF-UCLFligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0016922 TAS:BHF-UCLFligand-dependent nuclear receptor binding
GO:0042277 IEA:EnsemblFpeptide binding
GO:0000980 IDA:BHF-UCLFRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003705 IDA:BHF-UCLFRNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0001190 IDA:BHF-UCLFRNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0043565 IDA:UniProtKBFsequence-specific DNA binding
GO:0003700 TAS:ProtIncFsequence-specific DNA binding transcription factor activity
GO:0003707 IEA:EnsemblFsteroid hormone receptor activity
GO:0004887 IEA:InterProFthyroid hormone receptor activity
GO:0003713 TAS:ProtIncFtranscription coactivator activity
GO:0003714 TAS:ProtIncFtranscription corepressor activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0008206 IEA:EnsemblPbile acid metabolic process
GO:0071229 IDA:BHF-UCLPcellular response to acid chemical
GO:0071417 ISS:BHF-UCLPcellular response to organonitrogen compound
GO:0048565 IEA:EnsemblPdigestive tract development
GO:0010467 TAS:ReactomePgene expression
GO:0038185 IDA:UniProtKBPintracellular bile acid receptor signaling pathway
GO:0030522 ISS:BHF-UCLPintracellular receptor signaling pathway
GO:0070858 IDA:UniProtKBPnegative regulation of bile acid biosynthetic process
GO:0000122 ISS:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0001080 IC:BHF-UCLPnitrogen catabolite activation of transcription from RNA polymerase II promoter
GO:2001250 IEA:EnsemblPpositive regulation of ammonia assimilation cycle
GO:2000213 ISS:BHF-UCLPpositive regulation of glutamate metabolic process
GO:0045944 IMP:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0070857 TAS:BHF-UCLPregulation of bile acid biosynthetic process
GO:0006109 IEA:EnsemblPregulation of carbohydrate metabolic process
GO:0090181 TAS:BHF-UCLPregulation of cholesterol metabolic process
GO:0034255 ISS:BHF-UCLPregulation of urea metabolic process
GO:0009749 IEA:EnsemblPresponse to glucose
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0007165 TAS:ProtIncPsignal transduction
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04976Bile secretion
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116145PPARA activates gene expression