LMPD Database

LMP000247

Gene Information

Entrez Gene ID	5465
Gene Name	peroxisome proliferator-activated receptor alpha
Gene Symbol	PPARA
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005634	IEA:UniProtKB-KW	C	nucleus
GO:0004879	IEA:Ensembl	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008289	IEA:Ensembl	F	lipid binding
GO:0001190	IEA:Ensembl	F	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0043565	IEA:Ensembl	F	sequence-specific DNA binding
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0035095	IEA:Ensembl	P	behavioral response to nicotine
GO:0032922	IEA:Ensembl	P	circadian regulation of gene expression
GO:0070166	IEA:Ensembl	P	enamel mineralization
GO:0008544	IEA:Ensembl	P	epidermis development
GO:0006631	IEA:Ensembl	P	fatty acid metabolic process
GO:0007507	IEA:Ensembl	P	heart development
GO:0042157	IEA:Ensembl	P	lipoprotein metabolic process
GO:0032099	IEA:Ensembl	P	negative regulation of appetite
GO:0045776	IEA:Ensembl	P	negative regulation of blood pressure
GO:1901215	IEA:Ensembl	P	negative regulation of neuron death
GO:0032091	IEA:Ensembl	P	negative regulation of protein binding
GO:2000678	IEA:Ensembl	P	negative regulation of transcription regulatory region DNA binding
GO:0046321	IEA:Ensembl	P	positive regulation of fatty acid oxidation
GO:0045722	IEA:Ensembl	P	positive regulation of gluconeogenesis
GO:0042752	IEA:Ensembl	P	regulation of circadian rhythm
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0032868	IEA:Ensembl	P	response to insulin
GO:0042060	IEA:Ensembl	P	wound healing

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04024	cAMP signaling pathway
hsa04932	Non-alcoholic fatty liver disease (NAFLD)