LMPD Database

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LMP013467

UniProt Annotations

Entry Information
Gene Namecrystallin, zeta (quinone reductase)
Protein EntryQOR_RAT
UniProt IDQ6AYT0
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityNADPH + 2 quinone = NADP(+) + 2 semiquinone.
FunctionDoes not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding (By similarity)
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
Subcellular LocationCytoplasm .
SubunitHomotetramer