LMPD Database

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LMP012755

UniProt Annotations

Entry Information
Gene Nameinositol polyphosphate-4-phosphatase, type I
Protein EntryINP4A_RAT
UniProt IDQ62784
SpeciesRat
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; Synonyms=Alpha1; IsoId=Q62784-1; Sequence=Displayed; Name=2; Synonyms=Alpha2; IsoId=Q62784-2; Sequence=VSP_015247;
Catalytic Activity1-phosphatidyl-myo-inositol 3,4-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
FunctionCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate.
PathwaySignal transduction; phosphatidylinositol signaling pathway.
SimilarityBelongs to the inositol 3,4-bisphosphate 4-phosphatase family
SimilarityContains 1 C2 domain
Tissue SpecificityWidely expressed. Expressed at highest levels in the brain, heart and skeletal muscle