LMPD Database

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LMP012447

UniProt Annotations

Entry Information
Gene NameGNAS complex locus
Protein EntryGNAS3_RAT
UniProt IDQ792G6
SpeciesRat
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=5; Name=Nesp55 ; IsoId=Q792G6-1; Sequence=Displayed; Note=Shares no sequence similarity with other isoforms due to a novel first exon containing the entire reading frame spliced to shared exon 2 so that exons 2-13 make up the 3'-UTR.; Name=XLas-1; IsoId=Q63803-1; Sequence=External; Name=Gnas-1 ; IsoId=P63095-1; Sequence=External; Name=Gnas-2 ; IsoId=P63095-2; Sequence=External; Name=Gnas-3 {ECO:0000305}; Synonyms=GsaN1 ; IsoId=P63095-3; Sequence=External;
MiscellaneousThe GNAS locus is imprinted in a complex manner, giving rise to distinct paternally, maternally and biallelically expressed proteins. The XLas isoforms are paternally derived, the Gnas isoforms are biallelically derived and the Nesp55 isoforms are maternally derived.
PtmBinds keratan sulfate chains
PtmMay be proteolytically processed to give rise to a number of active peptides
SimilarityBelongs to the NESP55 family
Subcellular LocationCytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Secreted . Note=Neuroendocrine secretory granules