LMPD Database

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LMP012357

UniProt Annotations

Entry Information
Gene Namecoenzyme Q4
Protein Entry
UniProt IDQ9Y3A0
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y3A0-1; Sequence=Displayed; Name=2; IsoId=Q9Y3A0-2; Sequence=VSP_036866;
FunctionComponent of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. {ECO:0000255|HAMAP- Rule:MF_03111, ECO:0000269|PubMed:18474229}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis
SimilarityBelongs to the COQ4 family. {ECO:0000255|HAMAP- Rule:MF_03111}.
Subcellular LocationIsoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
SubunitComponent of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9
Tissue SpecificityExpressed ubiquitously, but at high levels in liver, lung and pancreas