LMPD Database

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LMP012348

Gene Information

Entrez Gene ID9370
Gene Nameadiponectin, C1Q and collagen domain containing
Gene SymbolADIPOQ
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0005581 IEA:UniProtKB-KWCcollagen trimer
GO:0005783 ISS:UniProtKBCendoplasmic reticulum
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005125 NAS:BHF-UCLFcytokine activity
GO:0005179 IDA:BHF-UCLFhormone activity
GO:0042802 TAS:BHF-UCLFidentical protein binding
GO:0042803 IPI:BHF-UCLFprotein homodimerization activity
GO:0005102 ISS:UniProtKBFreceptor binding
GO:0033691 IDA:UniProtKBFsialic acid binding
GO:0033211 IEA:EnsemblPadiponectin-activated signaling pathway
GO:0050873 ISS:UniProtKBPbrown fat cell differentiation
GO:0071320 IEA:EnsemblPcellular response to cAMP
GO:0035690 ISS:UniProtKBPcellular response to drug
GO:0071872 IEA:EnsemblPcellular response to epinephrine stimulus
GO:0032869 ISS:UniProtKBPcellular response to insulin stimulus
GO:0007623 IEA:EnsemblPcircadian rhythm
GO:0070994 ISS:UniProtKBPdetection of oxidative stress
GO:0006635 ISS:UniProtKBPfatty acid beta-oxidation
GO:0019395 ISS:UniProtKBPfatty acid oxidation
GO:0006091 TAS:ProtIncPgeneration of precursor metabolites and energy
GO:0042593 ISS:UniProtKBPglucose homeostasis
GO:0006006 ISS:UniProtKBPglucose metabolic process
GO:0034383 IDA:BHF-UCLPlow-density lipoprotein particle clearance
GO:0051899 IEA:EnsemblPmembrane depolarization
GO:0060081 IEA:EnsemblPmembrane hyperpolarization
GO:0045776 IDA:UniProtKBPnegative regulation of blood pressure
GO:0030336 ISS:UniProtKBPnegative regulation of cell migration
GO:2000279 IDA:UniProtKBPnegative regulation of DNA biosynthetic process
GO:0070373 IDA:UniProtKBPnegative regulation of ERK1 and ERK2 cascade
GO:0045599 IDA:BHF-UCLPnegative regulation of fat cell differentiation
GO:0045721 ISS:BHF-UCLPnegative regulation of gluconeogenesis
GO:0030853 IDA:BHF-UCLPnegative regulation of granulocyte differentiation
GO:0034115 IDA:BHF-UCLPnegative regulation of heterotypic cell-cell adhesion
GO:0046888 IEA:EnsemblPnegative regulation of hormone secretion
GO:0043124 IDA:BHF-UCLPnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050728 ISS:UniProtKBPnegative regulation of inflammatory response
GO:0090317 IDA:UniProtKBPnegative regulation of intracellular protein transport
GO:0045715 IDA:BHF-UCLPnegative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0010745 IDA:BHF-UCLPnegative regulation of macrophage derived foam cell differentiation
GO:0045650 IDA:BHF-UCLPnegative regulation of macrophage differentiation
GO:0043407 ISS:UniProtKBPnegative regulation of MAP kinase activity
GO:2000590 ISS:UniProtKBPnegative regulation of metanephric mesenchymal cell migration
GO:0050765 IDA:BHF-UCLPnegative regulation of phagocytosis
GO:2000584 ISS:UniProtKBPnegative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0010642 IDA:UniProtKBPnegative regulation of platelet-derived growth factor receptor signaling pathway
GO:0031953 IDA:UniProtKBPnegative regulation of protein autophosphorylation
GO:1900121 IDA:UniProtKBPnegative regulation of receptor binding
GO:0014912 IDA:UniProtKBPnegative regulation of smooth muscle cell migration
GO:0048662 IDA:UniProtKBPnegative regulation of smooth muscle cell proliferation
GO:0050805 IDA:UniProtKBPnegative regulation of synaptic transmission
GO:0045892 IDA:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0010804 IDA:BHF-UCLPnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032720 IDA:BHF-UCLPnegative regulation of tumor necrosis factor production
GO:0045777 IEA:EnsemblPpositive regulation of blood pressure
GO:2000481 IDA:UniProtKBPpositive regulation of cAMP-dependent protein kinase activity
GO:0032270 IDA:BHF-UCLPpositive regulation of cellular protein metabolic process
GO:0010875 IDA:BHF-UCLPpositive regulation of cholesterol efflux
GO:0045923 ISS:BHF-UCLPpositive regulation of fatty acid metabolic process
GO:0046326 ISS:BHF-UCLPpositive regulation of glucose import
GO:2000467 ISS:UniProtKBPpositive regulation of glycogen (starch) synthase activity
GO:0043123 ISS:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032757 IDA:UniProtKBPpositive regulation of interleukin-8 production
GO:2000478 ISS:UniProtKBPpositive regulation of metanephric glomerular visceral epithelial cell development
GO:0071639 IDA:UniProtKBPpositive regulation of monocyte chemotactic protein-1 production
GO:0033034 IDA:BHF-UCLPpositive regulation of myeloid cell apoptotic process
GO:0050731 IEA:EnsemblPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0010739 IDA:BHF-UCLPpositive regulation of protein kinase A signaling
GO:0001934 IDA:UniProtKBPpositive regulation of protein phosphorylation
GO:2000534 IDA:UniProtKBPpositive regulation of renal albumin absorption
GO:0009967 ISS:BHF-UCLPpositive regulation of signal transduction
GO:0070208 IEA:EnsemblPprotein heterotrimerization
GO:0051260 ISS:UniProtKBPprotein homooligomerization
GO:0072659 IDA:UniProtKBPprotein localization to plasma membrane
GO:0010906 IDA:UniProtKBPregulation of glucose metabolic process
GO:0014823 IEA:EnsemblPresponse to activity
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0051384 IEA:EnsemblPresponse to glucocorticoid
GO:0009749 ISS:BHF-UCLPresponse to glucose
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0070543 IEA:EnsemblPresponse to linoleic acid
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0009744 IEA:EnsemblPresponse to sucrose
GO:0034612 IDA:BHF-UCLPresponse to tumor necrosis factor
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04920Adipocytokine signaling pathway
ko04920Adipocytokine signaling pathway
hsa04152AMPK signaling pathway
ko04152AMPK signaling pathway
hsa04932Non-alcoholic fatty liver disease (NAFLD)
ko04932Non-alcoholic fatty liver disease (NAFLD)
hsa03320PPAR signaling pathway
ko03320PPAR signaling pathway
hsa04930Type II diabetes mellitus
ko04930Type II diabetes mellitus
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111045Developmental Biology
REACT_27161Transcriptional regulation of white adipocyte differentiation