LMPD Database

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LMP010920

UniProt Annotations

Entry Information
Gene NameBiotin/lipoate A/B protein ligase family
Protein EntryLIP2P_ARATH
UniProt IDQ948J9
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityLipoyl-[acyl-carrier-protein] + apo-protein = holo-protein + acyl-carrier-protein.
FunctionCatalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier-protein as a source of lipoyl groups, although octanoyl groups from octanoyl-ACP can also be transferred to the lipoyl domain of apoproteins. {ECO:0000269|PubMed:11602263}.
PathwayProtein modification; protein lipoylation via endogenous pathway.
Sequence CautionSequence=CAA18187.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31060 has been split into 2 genes: At4g31060 and At4g31050.; Evidence={ECO:0000305}; Sequence=CAB79824.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31060 has been split into 2 genes: At4g31060 and At4g31050.; Evidence={ECO:0000305};
SimilarityBelongs to the LipB family. {ECO:0000305}.
SimilarityContains 1 BPL/LPL catalytic domain. {ECO:0000255|PROSITE-ProRule:PRU01067}.
Subcellular LocationPlastid, chloroplast {ECO:0000269|PubMed:11602263}.
Tissue SpecificityExpressed in roots, leaves and flowers. {ECO:0000269|PubMed:11602263}.