LMPD Database

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LMP010881

UniProt Annotations

Entry Information
Gene Namephospholipase D alpha 3
Protein EntryPLDZ1_ARATH
UniProt IDP58766
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityA phosphatidylcholine + H(2)O = choline + a phosphatidate.
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250};
DomainC2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. A lower affinity toward calcium can be anticipated for PLD alpha due to the absence of two potential calcium ligands.
FunctionHydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.
InductionRegulated by the transcription factors NAC045 and NAC086. {ECO:0000269|PubMed:25081480}.
SimilarityBelongs to the phospholipase D family. C2-PLD subfamily. {ECO:0000305}.
SimilarityContains 1 C2 domain. {ECO:0000305}.
SimilarityContains 2 PLD phosphodiesterase domains. {ECO:0000255|PROSITE-ProRule:PRU00153}.
Subcellular LocationCytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue SpecificityExpressed in the sieve elements. {ECO:0000269|PubMed:25081480}.