LMPD Database

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LMP010760

UniProt Annotations

Entry Information
Gene Nameperoxin 10
Protein EntryPEX10_ARATH
UniProt IDQ9SYU4
SpeciesArabidopsis
Comments
Comment typeDescription
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:23336935};
Developmental StageIncreased expression in early post- germinative growth.
Disruption PhenotypeEmbryo lethality at the heart stage. {ECO:0000269|PubMed:12883010, ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:17215364}.
FunctionInvolved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. {ECO:0000269|PubMed:12883010, ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:17215364, ECO:0000269|PubMed:17478547, ECO:0000269|PubMed:20679226, ECO:0000269|PubMed:23336935}.
InductionUp-regulated by hydrogen peroxide. {ECO:0000269|PubMed:11118212}.
InteractionQ9SRQ3:PEX19-1; NbExp=2; IntAct=EBI-1151983, EBI-1151789;
MiscellaneousTravels directly from the cytosol to the peroxisomes.
Sequence CautionSequence=AAM14959.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the pex2/pex10/pex12 family. {ECO:0000305}.
SimilarityContains 1 RING-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00175}.
Subcellular LocationPeroxisome {ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:16169966}. Peroxisome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
SubunitInteracts (via C-terminus) with PEX19-1. {ECO:0000269|PubMed:16923726}.
Tissue SpecificityExpressed in roots, stems, leaves, flowers and siliques. {ECO:0000269|PubMed:14576288}.
Web ResourceName=PlantsUBQ; Note=A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants; URL="http://plantsubq.genomics.purdue.edu/";