LMPD Database

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LMP010736

UniProt Annotations

Entry Information
Gene Namepatatin-like protein 6
Protein EntryPLP7_ARATH
UniProt IDQ9SV43
SpeciesArabidopsis
Comments
Comment typeDescription
CautionLacks the conserved Asp residue expected to act as the active site proton acceptor. {ECO:0000305}.
Disruption PhenotypeIncreased length of leaves, petioles, hypocotyls, primary roots and root hairs. Changes in lipid levels and composition. {ECO:0000269|PubMed:21447788}.
DomainThe nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage. {ECO:0000250}.
FunctionPossesses non-specific lipolytic acyl hydrolase (LAH) activity. Catalyzes the hydrolysis of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), and the phoshpolipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidic acid (PA), phosphatidylserine (PS). Favors the release of fatty acid at the sn-2 position for PC. Possesses acyl- CoA thioesterase activity. Negatively affects disease resistance to the necrotic fungal pathogen Botrytis cinerea and the avirulent bacteria Pseudomonas syringae by promoting cell death and reducing the efficiency of the hypersensitive response, respectively. However, PLP2 contributes to resistance to cucumber mosaic virus (CMV), an obligate parasite inducing hypersensitive response. May negatively regulate oxylipin production, possibly via participating in membrane repair that includes removal of oxidatively modified lipids. Enzymatic products of PLP2 may influence cellulose content and cell elongation. {ECO:0000269|PubMed:21447788}.
InductionBy the fungal pathogen B.cinerea and an avirulent strain of P.syringae pv tomato. {ECO:0000269|PubMed:16297072, ECO:0000269|PubMed:21447788}.
MiscellaneousPlants over-expressing PLP7 have decreased cellulose content and mechanical strength. {ECO:0000305|PubMed:21447788}.
SimilarityBelongs to the patatin family. {ECO:0000305}.
SimilarityContains 1 patatin domain. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000305|PubMed:21447788}; Peripheral membrane protein {ECO:0000305|PubMed:21447788}. Note=Associated with the plasma membrane.
Tissue SpecificityHighly expressed in roots and at lower levels in leaves, stems, flowers and siliques. {ECO:0000269|PubMed:21447788}.