LMPD Database

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LMP010693

UniProt Annotations

Entry Information
Gene Namelipoyltransferase 2
Protein EntryLIPB_ARATH
UniProt IDQ9SXP7
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityOctanoyl-[acyl-carrier-protein] + protein = protein N(6)-(octanoyl)lysine + [acyl-carrier-protein].
FunctionCatalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (Probable). {ECO:0000305|PubMed:11427685}.
MiscellaneousIn the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon- amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. {ECO:0000250}.
PathwayProtein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier- protein]: step 1/2.
Sequence CautionSequence=AAB80636.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g04640 has been split into 2 genes: At1g04635 and At1g04640.; Evidence={ECO:0000305};
SimilarityBelongs to the LipB family. {ECO:0000305}.
SimilarityContains 1 BPL/LPL catalytic domain. {ECO:0000255|PROSITE-ProRule:PRU01067}.
Tissue SpecificityExpressed in leaves. {ECO:0000269|PubMed:11427685}.