LMPD Database

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LMP010049

UniProt Annotations

Entry Information
Gene Nameclathrin coat assembly protein AP180
Protein EntryAP180_ARATH
UniProt IDQ9ZVN6
SpeciesArabidopsis
Comments
Comment typeDescription
FunctionAdaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia promotes their assembly into 70-90 nm coats cages. {ECO:0000269|PubMed:15054111}.
InteractionQ8LPK4:ALPHAC-AD; NbExp=2; IntAct=EBI-2366853, EBI-2366827;
SimilarityContains 1 ENTH (epsin N-terminal homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00243}.
Subcellular LocationMembrane, clathrin-coated pit {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, clathrin- coated vesicle {ECO:0000250}. Note=Colocalized with clathrin in the Golgi area. {ECO:0000250}.
SubunitInteracts with ALPHAC-AD and clathrin. {ECO:0000269|PubMed:15054111}.