LMPD Database

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LMP010017

UniProt Annotations

Entry Information
Gene Namephosphatidylglycerolphosphate synthase 2
Protein EntryPGPS2_ARATH
UniProt IDQ9M2W3
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=62 uM for glycerol-3-phosphate {ECO:0000269|PubMed:11741606}; KM=17 uM for CDP-dipalmitoylglycerol {ECO:0000269|PubMed:11741606}; pH dependence: Optimum pH is 8.5. {ECO:0000269|PubMed:11741606};
Catalytic ActivityCDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate. {ECO:0000269|PubMed:11741606}.
CofactorName=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:11741606};
FunctionThis protein catalyzes the committed step to the synthesis of the acidic phospholipids. {ECO:0000269|PubMed:11741606}.
PathwayPhospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}.
Subcellular LocationMicrosome membrane {ECO:0000305|PubMed:11741606}; Multi-pass membrane protein {ECO:0000305}.