LMPD Database

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LMP009955

UniProt Annotations

Entry Information
Gene NameBON association protein 1
Protein EntryBAP1_ARATH
UniProt IDQ941L2
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=1; Comment=A number of isoforms are produced. According to EST sequences.; Name=1; IsoId=Q941L2-1; Sequence=Displayed;
Disruption PhenotypeDwarf, twisted leaves and enhanced disease resistance to bacterial and oomycete pathogens in cv. Columbia when grown under constant loght at 22 degrees Celsius. No visible phenotype when grown at 28 degrees Celsius. Accelerated hypersensitive response (HR). Bap1 and bap2 double mutant is seedling lethal. {ECO:0000269|PubMed:17018034, ECO:0000269|PubMed:17631528}.
FunctionNegative regulator of cell death and defense responses. Exhibits calcium-dependent phospholipid binding properties. {ECO:0000269|PubMed:17018034, ECO:0000269|PubMed:17631528}.
InductionDown-regulated by high temperature. Up-regulated by salicylic acid, AgNO(3), chitin, cycloheximide, ozone, syringolin, salt stress and upon pathogen or nematode infection. {ECO:0000269|PubMed:11544183, ECO:0000269|PubMed:17018034, ECO:0000269|PubMed:17631528}.
InteractionQ5S1W2:BON2; NbExp=3; IntAct=EBI-1606302, EBI-1606334;
MiscellaneousOverexpression of BAP1 can suppress a defect in BON1 and confers more susceptibility to virulent pathogens.
Sequence CautionSequence=AAM64568.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAB71049.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
SimilarityContains 1 C2 domain. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000269|PubMed:17018034}; Peripheral membrane protein {ECO:0000269|PubMed:17018034}.
SubunitInteracts with BON1 (via VWA domain), BON2 and BON3. {ECO:0000269|PubMed:11544183, ECO:0000269|PubMed:17018034, ECO:0000269|PubMed:17631528, ECO:0000269|PubMed:20634289}.
Tissue SpecificityExpressed in roots, leaves, stems and flowers. {ECO:0000269|PubMed:11544183}.