LMPD Database

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LMP009799

UniProt Annotations

Entry Information
Gene NameADP-ribosylation factor GTPase-activating protein AGD12
Protein EntryAGD12_ARATH
UniProt IDQ9FVJ3
SpeciesArabidopsis
Comments
Comment typeDescription
DomainThe C2 domain binds anionic phospholipids promiscuously in the presence of calcium while the N-terminal region (1-174) show a specific affinity for phosphatidylinositol 3-monophosohate.
FunctionGTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Binds phosphatidylinositol 3-monophosohate (PI-3-P) and anionic phospholipids.
Sequence CautionSequence=CAA17535.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB79116.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityContains 1 Arf-GAP domain. {ECO:0000255|PROSITE- ProRule:PRU00288}.
SimilarityContains 1 C2 domain. {ECO:0000255|PROSITE- ProRule:PRU00041}.
Subcellular LocationGolgi apparatus {ECO:0000269|PubMed:11202441}. Cell membrane {ECO:0000269|PubMed:11202441}.
Tissue SpecificityExpressed in roots, leaves, flowers and siliques. Low levels of expression in seeds and stems. {ECO:0000269|PubMed:11202441}.