LMPD Database

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LMP007752

UniProt Annotations

Entry Information
Gene Name3-octaprenyl-4-hydroxybenzoate decarboxylase
Protein EntryUBID_ECOLI
UniProt IDP0AAB4
SpeciesE. coli
Comments
Comment typeDescription
CofactorName=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:782527}; Note=Divalent metal ions. Preferably manganese. {ECO:0000269|PubMed:782527};
Enzyme RegulationRequires phospholipid, a metal ion, dithiothreitol and at least one other so far unidentified soluble cofactor for maximal activity. Inhibited by EDTA. {ECO:0000269|PubMed:782527}.
FunctionCatalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol. {ECO:0000269|PubMed:782527}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000269|PubMed:782527}.
Sequence CautionSequence=AAA67639.1; Type=Frameshift; Positions=380; Evidence={ECO:0000305}; Sequence=CAA46146.1; Type=Frameshift; Positions=376; Evidence={ECO:0000305};
SimilarityBelongs to the UbiD family. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000305|PubMed:782527}; Peripheral membrane protein {ECO:0000305|PubMed:782527}.
SubunitHomohexamer. {ECO:0000305|PubMed:782527}.