LMPD Database

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LMP007645

UniProt Annotations

Entry Information
Gene Namephosphatidylglycerophosphate synthetase
Protein EntryPGSA_ECOLI
UniProt IDP0ABF8
SpeciesE. coli
Comments
Comment typeDescription
Catalytic ActivityCDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate.
FunctionThis protein catalyzes the committed step to the synthesis of the acidic phospholipids.
PathwayPhospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}.
Subcellular LocationCell inner membrane; Multi-pass membrane protein.