LMPD Database

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LMP007364

UniProt Annotations

Entry Information
Gene NameLys5p
Protein EntryLYS5_YEAST
UniProt IDP50113
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=1 uM for CoA {ECO:0000269|PubMed:10320345}; KM=1 uM for alpha-aminoadipate reductase PCP fragment {ECO:0000269|PubMed:10320345};
Catalytic ActivityCoA-(4'-phosphopantetheine) + apo-[acyl- carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl- carrier-protein].
FunctionCatalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity. {ECO:0000269|PubMed:10320345}.
MiscellaneousPresent with 623 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the P-Pant transferase superfamily. AcpS family. {ECO:0000305}.