LMPD Database

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LMP007270

UniProt Annotations

Entry Information
Gene Nameinositol monophosphate 1-phosphatase INM2
Protein EntryINM2_YEAST
UniProt IDQ05533
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.12 mM for inositol 1-phosphate {ECO:0000269|PubMed:10096091}; Vmax=16 umol/min/mg enzyme for inositol 1-phosphate {ECO:0000269|PubMed:10096091};
Biophysicochemical PropertiesKinetic parameters: KM=0.12 mM for inositol 1-phosphate ; Vmax=16 umol/min/mg enzyme for inositol 1-phosphate ;
Catalytic ActivityMyo-inositol phosphate + H(2)O = myo-inositol + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420;
Enzyme RegulationInhibited by Li(+) and Na(+)
Enzyme RegulationInhibited by Li(+) and Na(+). {ECO:0000269|PubMed:10096091}.
FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling
FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling. {ECO:0000269|PubMed:10096091, ECO:0000269|PubMed:12593845}.
PathwayPolyol metabolism; myo-inositol biosynthesis; myo- inositol from D-glucose 6-phosphate: step 2/2.
SimilarityBelongs to the inositol monophosphatase family
SimilarityBelongs to the inositol monophosphatase family. {ECO:0000305}.