LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007237

UniProt Annotations

Entry Information
Gene NamePsy2p
Protein EntryPP4R3_YEAST
UniProt IDP40164
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionCore regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint
FunctionCore regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint. {ECO:0000269|PubMed:16299494}.
InteractionP38193:PSY4; NbExp=8; IntAct=EBI-29107, EBI-21239; P40454:RRD1; NbExp=3; IntAct=EBI-29107, EBI-25278; P27692:SPT5; NbExp=6; IntAct=EBI-29107, EBI-17937;
MiscellaneousPresent with 7010 molecules/cell in log phase SD medium
MiscellaneousPresent with 7010 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Subcellular LocationNucleus .
Subcellular LocationNucleus {ECO:0000269|PubMed:14562095}.
SubunitRegulatory subunit 3 (R3) of the histone H2A phosphatase complex (HTP-C) consisting of PPH3, PSY2 and PSY4. Interacts with SPT4, SPT5 and TIP41. {ECO:0000269|PubMed:16085932, ECO:0000269|PubMed:16299494}.