LMPD Database

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LMP007213

UniProt Annotations

Entry Information
Gene Nameinositol monophosphate 1-phosphatase INM1
Protein EntryINM1_YEAST
UniProt IDP38710
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.08 mM for inositol 1-phosphate {ECO:0000269|PubMed:10096091}; Vmax=20 umol/min/mg enzyme for inositol 1-phosphate {ECO:0000269|PubMed:10096091};
Biophysicochemical PropertiesKinetic parameters: KM=0.08 mM for inositol 1-phosphate ; Vmax=20 umol/min/mg enzyme for inositol 1-phosphate ;
Catalytic ActivityMyo-inositol phosphate + H(2)O = myo-inositol + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420;
Enzyme RegulationInhibited by Li(+) and Na(+)
Enzyme RegulationInhibited by Li(+) and Na(+). {ECO:0000269|PubMed:10096091}.
FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides
FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. {ECO:0000250}.
MiscellaneousPresent with 2440 molecules/cell in log phase SD medium
MiscellaneousPresent with 2440 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayPolyol metabolism; myo-inositol biosynthesis; myo- inositol from D-glucose 6-phosphate: step 2/2.
SimilarityBelongs to the inositol monophosphatase family
SimilarityBelongs to the inositol monophosphatase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Subcellular LocationCytoplasm . Nucleus .