LMPD Database

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LMP007209

UniProt Annotations

Entry Information
Gene Name2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase
Protein EntryCOQ5_YEAST
UniProt IDP49017
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityS-adenosyl-L-methionine + 2-methoxy-6-all- trans-polyprenyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 6- methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol. {ECO:0000255|PROSITE-ProRule:PRU00940, ECO:0000269|PubMed:9083049}.
FunctionMethyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
MiscellaneousPresent with 8100 molecules/cell in log phase SD medium
MiscellaneousPresent with 8100 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis.
SimilarityBelongs to the class I-like SAM-binding methyltransferase superfamily. UbiE family. {ECO:0000255|PROSITE- ProRule:PRU00940}.
Subcellular LocationMitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:9083049}.