LMPD Database

LMP007125

UniProt Annotations

Entry Information
Gene NameCwh41p
Protein EntryCWH41_YEAST
UniProt IDP53008
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityExohydrolysis of the non-reducing terminal glucose residues in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
FunctionCleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor highly specifically. Seems to play a role in beta-1,6-glucan synthesis.
InteractionP53090:ARO8; NbExp=1; IntAct=EBI-5323, EBI-2042933; Q6Q5K6:HUG1; NbExp=1; IntAct=EBI-5323, EBI-392766; P21524:RNR1; NbExp=1; IntAct=EBI-5323, EBI-15234;
MiscellaneousPresent with 2840 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayGlycan metabolism; N-glycan degradation.
SimilarityBelongs to the glycosyl hydrolase 63 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Single-pass type II membrane protein.