LMPD Database

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LMP007093

UniProt Annotations

Entry Information
Gene Nameputative monooxygenase CAT5
Protein EntryCAT5_YEAST
UniProt IDP41735
SpeciesYeast (S288c)
Comments
Comment typeDescription
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250}; Note=Binds 2 iron ions per subunit. {ECO:0000250};
FunctionCentral metabolic regulator required for the derepression of PCK1, and thereby gluconeogenesis. Necessary for transcriptional activation of the CAT8 gene. Also involved in the control of expression of other enzymes of gluconeogenesis and those of respiration and the glyoxylate cycle. Also involved in one or more monooxygenase steps of ubiquinone biosynthesis. {ECO:0000269|PubMed:8557031, ECO:0000269|PubMed:8621692, ECO:0000269|PubMed:9452453}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis.
SimilarityBelongs to the COQ7 family. {ECO:0000305}.
Subcellular LocationMitochondrion inner membrane {ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:9452453}.