LMPD Database

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LMP007008

UniProt Annotations

Entry Information
Gene NameMet22p
Protein EntryMET22_YEAST
UniProt IDP32179
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityAdenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420;
FunctionConverts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. Involved in salt tolerance. Confers resistance to lithium.
InductionBy salt stress.
MiscellaneousPresent with 7330 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the inositol monophosphatase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.