LMPD Database

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LMP006943

UniProt Annotations

Entry Information
Gene NameCoq4p
Protein EntryCOQ4_YEAST
UniProt IDO13525
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionComponent of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111, ECO:0000269|PubMed:15548532, ECO:0000269|PubMed:17391640, ECO:0000269|PubMed:19022396}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03111}.
SimilarityBelongs to the COQ4 family. {ECO:0000255|HAMAP- Rule:MF_03111}.
Subcellular LocationMitochondrion inner membrane {ECO:0000255|HAMAP-Rule:MF_03111, ECO:0000269|PubMed:11469793, ECO:0000269|PubMed:14562095}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03111, ECO:0000269|PubMed:11469793, ECO:0000269|PubMed:14562095}; Matrix side {ECO:0000255|HAMAP- Rule:MF_03111, ECO:0000269|PubMed:11469793, ECO:0000269|PubMed:14562095}.
SubunitComponent of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with COQ3. {ECO:0000255|HAMAP-Rule:MF_03111, ECO:0000269|PubMed:15792955, ECO:0000269|PubMed:16624818, ECO:0000269|PubMed:17391640}.